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2020;6:eabc2487

indeed, recent data show that it alters the correct signaling of both phosphoinositide 3-kinase (PI3K)/Akt pathway and AR pathway, which coordinate carcinogenesis [68], EMT, metastasis and cancer progression in this tumor type [69,70,71,72]

They work best when combined with ongoing lifestyle modifications, including the dietary and exercise strategies discussed earlier

Reasons for differences in observed incidence are intensity of isocyanate exposure, criteria for diagnosis, mode of calculation, sensitizing capacity of different isocyanates, individual predisposition and confounding factors

FMO3 gene can affect the intensity of the symptoms